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PRODUCT DESCRIPTION
Most supplement strategies focus on building muscle. The dimension they ignore is stopping it from breaking down.
Muscle protein breakdown is a continuous process – and during intense training, caloric deficits, endurance blocks, or injury recovery, breakdown accelerates and outpaces synthesis. This is where athletes lose hard-earned muscle during cutting phases, high-volume training, and forced rest. HMB (Beta-Hydroxy Beta-Methylbutyrate) directly addresses this. A metabolite of leucine, it inhibits the ubiquitin-proteasome pathway that drives muscle protein degradation while simultaneously activating the mTOR pathway that promotes synthesis – working on both sides of the protein turnover equation at once.
The 5XL Nutrition HMB delivers 1000mg per serving in vegetarian capsules – consistent with the clinical research on HMB’s effects on muscle preservation, recovery, and anti-catabolism.
₹1,124 (25% off ₹1,499) | 60 capsules | Free shipping pan-India | Verify at the5xlnutrition.com/verify-product
Why Choose The 5XL Nutrition HMB?
- 1000mg – Research-Aligned Dose Per Serving: Clinical research on HMB primarily uses 3g daily across split doses. At 1000mg per capsule, 3 capsules deliver the full research dose – or 2 capsules for a maintenance-level anti-catabolic protocol.
- Dual Mechanism – Anti-Catabolic + Pro-Anabolic: Leucine activates mTOR (synthesis). HMB does this too – but also inhibits the ubiquitin-proteasome breakdown pathway simultaneously. The net result is a more favourable muscle protein balance than any single-direction supplement can achieve.
- Most Valuable During Caloric Deficit: When calories are restricted, the body increasingly uses muscle protein as fuel. HMB directly inhibits this breakdown pathway – preserving lean mass while fat loss proceeds. This is why it is used by competitive bodybuilders during contest prep and by clinical populations managing muscle wasting.
- Vegetarian, Transparent, GMP Certified: HPMC vegetarian capsule. No fillers, no proprietary blends, no amino spiking. Every ingredient disclosed. Third-party tested for purity and potency.
Key Benefits of HMB
- Prevents Muscle Protein Breakdown: Direct inhibition of the ubiquitin-proteasome pathway – the cellular machinery that degrades muscle proteins during caloric deficits, high-volume training, endurance blocks, and inactivity. The primary and most clinically validated benefit of HMB.
- Reduces DOMS and Exercise-Induced Muscle Damage: Multiple RCTs document reductions in post-exercise soreness and creatine kinase elevation with HMB. Less muscle damage means higher training frequency, more consistent performance, and better recovery between sessions.
- Preserves Lean Mass During Cutting: One of the few supplements with specific clinical evidence for lean muscle preservation during energy restriction. Research shows HMB users maintain muscle mass and strength during caloric deficits that cause measurable muscle loss in placebo groups.
- Supports Strength Development: By reducing breakdown between sessions, each workout’s protein synthesis response accumulates more effectively. Studies consistently show greater strength gains over 3-12 week training periods – most significantly in beginners and those returning from detraining.
- Combats Sarcopenia in Older Adults: Specifically studied in elderly populations for age-related muscle loss, with consistent findings of improved lean mass retention, strength, and functional capacity – with or without resistance training.
- Synergistic with Protein and Creatine: HMB + Whey Protein + Creatine covers all three pillars simultaneously – protein synthesis stimulation (whey), cellular energy and strength (creatine), and muscle protein breakdown prevention (HMB). The most complete lean muscle stack available.
Nutritional Information (Per serving)
Nutrients | Quantity Per Serving | %RDA* |
Calcium Hydroxymethylbutyrate | 1000mg | – |
Vitamin D (cholecalciferol) Animal Source | 500IU | 83 |
Energy | 0kcal | – |
Protein | 0g | – |
Carbohydrates | 0g | – |
Total sugar | 0g | – |
Added sugar | 0g | – |
Total fat | 0g | – |
Cholesterol | 0mg | – |
Sodium | 0mg | – |
How to Use HMB
Take 2-3 capsules daily. 3 capsules (3g) is recommended for cutting phases, endurance training, or significant anti-catabolic need. 2 capsules is appropriate for general recovery and muscle preservation.
Timing | Rationale |
Pre-workout (30-60 min before) | Peak HMB levels during exercise-induced damage |
Post-workout | Supports recovery initiation window |
Split: 1 pre + 1 post + 1 with dinner | Optimal for full 3g/day research protocol |
With meals on rest days | Maintains steady anti-catabolic protection daily |
- For the full 3g protocol: 1 capsule with breakfast, 1 pre-workout, 1 post-workout or with dinner
- HMB is cumulative – daily consistency including rest days is essential for efficacy
- Stack with Creatine Monohydrate + Whey Protein for the most complete lean muscle building and preservation stack
What to expect: Weeks 1-2: reduced DOMS after intense sessions. Weeks 2-3: improved recovery and maintained strength across the training week. Weeks 4-6: measurable lean mass preservation during a deficit. Weeks 8-12: improved lean-to-fat ratio and more consistent strength development.
FAQs
What is the price and how long does one bottle last?
₹1,124 – 25% off ₹1,499. 60 capsules – 30 days at 2 capsules/day or 20 days at the full 3 capsules/day. Free shipping pan-India from the5xlnutrition.com.
What is HMB and how is it different from leucine?
HMB is a metabolite of leucine. Leucine activates mTOR – the anabolic signal for muscle protein synthesis. HMB does this too, but also inhibits the ubiquitin-proteasome breakdown pathway – the side of muscle metabolism leucine alone does not address. Think of leucine as the builder and HMB as the barrier against demolition.
How does HMB help during a cutting phase?
Caloric restriction elevates muscle protein breakdown as the body uses muscle for fuel. HMB directly inhibits this pathway – preserving lean mass while fat loss proceeds normally. Clinical research at 3g daily during energy restriction documents significantly better lean mass retention versus placebo.
Can older adults take HMB for sarcopenia?
Yes, one of HMB’s most validated applications. Multiple RCTs in elderly populations show significant improvements in lean mass, strength, and functional capacity. As muscle protein synthesis becomes less responsive to protein intake with age, HMB’s anti-catabolic action provides targeted support for maintaining muscle function.
Can beginners benefit from HMB?
Yes, research shows the largest effect sizes in untrained individuals, where exercise-induced protein turnover rates are highest. For someone new to resistance training, HMB may accelerate the initial adaptation phase by reducing breakdown alongside the new training stimulus.
How do I verify my HMB is genuine?
Every bottle includes a unique authenticity code. Visit the5xlnutrition.com/verify-product and confirm in under 30 seconds. Always verify before your first capsule.
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